Three of Wiesbaden's boroughs were part of the city of Mainz until 1945, and still bear the designation 'Mainz' in their names-the so-called AKK-boroughs of Mainz-Amöneburg, Mainz-Kastel, and Mainz-Kostheim. Wiesbaden lies in the Rheingau wine-growing region, one of Germany's 13 wine regions. The city is located on the Rhine, at the foothills of the Taunus, opposite the Rhineland-Palatine capital of Mainz, and the city centre is located in the wide valley of the small Salzbach stream. This conurbation is in turn embedded in the Rhine-Main Metropolitan Region-Germany's second-largest metropolitan region after Rhine-Ruhr-which also includes the nearby cities of Frankfurt am Main, Darmstadt, Offenbach am Main, and Hanau, and has a combined population exceeding 5.8 million. Wiesbaden forms a conurbation with a population of around 500,000 with the neighbouring city of Mainz. With around 283,000 inhabitants, it is Germany's 24th-largest city.

'meadow baths') is the capital of the German state of Hesse, and the second-largest Hessian city after Frankfurt am Main.

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